Medial Border of Laparoscopic D3 Lymphadenectomy for Right Colon Cancer

the Medial Border Along the Left Side of SMA Versus the Left Side of SMV in Laparoscopic D3 Lymphadenectomy for Right Colon Cancer, a Prospective Cohort Study

This study investigats the gastrointestinal functional outcomes of laparoscopic D3 lymphadenectomy for right colon cancer with the medial border along the left side of superior mesenteric artery (SMA) versus the left side of superior mesenteric vein (SMV). This is a single center, prospective cohort study with a sample size of 264 patients. The primary endpoint is the incidence of diarrhea (evaluated using the Diarrhea Assessment Scale) one month after surgery.

Inclusion Criteria:

• Age between 18 and 75 years
• American Society of Anesthesiologists (ASA) score I to III
• A biopsy proven histological diagnosis of colorectal carcinoma
• tumor located at right half of colon
• Undergoing laparoscopic right hemi-colectomy
• preoperative staging cT2-4aN0M0 or cTanyN+M0
• willing to participate and informed consent signed

Exclusion Criteria:

• Pregnant or lactating women
• Synchronous colorectal carcinoma
• History of colorectal cancer or other malignant tumors
• Clinical evidence of metastasis
• Preoperative staging cT1N0 or cT4bNany
• Emergency procedure