Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of this study is to determine if microRNA's have role in predicting multicentricity in breast cancer. If a specific microRNA will be found to be related with multicentricity, it will help us to make appropriate decisions on the treatment of patients with multicentric breast cancer.
In the study that will be held at Bezmialem Vakif University Medical Faculty, General Surgery Department, 20 unifocal and 20 multifocal breast cancer patients will be included. Tissues will be taken from both tumoral and normal breast tissues and they will be saved in microRNA later solution under -80°C. Then, 84 microRNA's will be studied in these tissues to see if they express any of these microRNA's.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| unifocal breast cancer | Active Comparator | patients having unifocal breast cancer |
|
| multicentric breast cancer | Active Comparator | patients having multicentric breast cancer |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| miRNA | Genetic | miRNA's expressed in breast cancer |
|
| Measure | Description | Time Frame |
|---|---|---|
| MicroRNA's in multicentric breast cancer | Evaluation of 84 microRNA's in patients with multicentric breast cancer | April 2014 |
| Measure | Description | Time Frame |
|---|---|---|
| Treatment plan according to the detected microRNA in patients with multicentric breast cancer | If a specific microRNA will be detected in patients with multicentric breast cancer, treatment plan will be individualized according to the detected microRNA | April 2014 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bezmialem Vakif University | Istanbul | 34306 | Turkey (Türkiye) |
Not provided
| ID | Term |
|---|---|
| D009369 | Neoplasms |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D035683 | MicroRNAs |
| ID | Term |
|---|---|
| D016372 | RNA, Antisense |
| D016375 | Antisense Elements (Genetics) |
| D009706 | Nucleic Acids, Nucleotides, and Nucleosides |
| D012313 | RNA |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| D009696 | Nucleic Acids |
| D058727 | RNA, Small Untranslated |
| D022661 | RNA, Untranslated |