Angelman Syndrome Natural History Study

Angelman Syndrome Natural History Study

The goal of this study is to conduct a prospective, longitudinal natural history study of children and adults with Angelman Syndrome using investigator-observed and parent-reported outcome measures to obtain data that will be useful for future clinical trials.

The overall goal is to increase our understanding of the long-term natural history of Angelman syndrome and obtain Angelman-specific norms for outcome measures that can be used in clinical trials, ultimately improving the care of individuals with Angelman syndrome.

Inclusion Criteria:

• Molecular diagnosis of Angelman syndrome

Exclusion Criteria:

• Presence of another condition, unrelated to Angelman syndrome, that affects neurodevelopment