Acute Effects of LBBP Versus BVP for CRT

Acute Effects of Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy

The study was designed to compare the acute effects of left bundle branch pacing (LBBP) with biventricular pacing (BVP) in patients with left ventricular ejection fraction (LVEF) <=35% with left bundle branch block (LBBB).

The metrics include electrocardiographic, echocardiographic and hemodynamic parameters to evaluate and compare LBBP with BVP for resynchronization therapy in patients with heart failure and LBBB.

Inclusion Criteria:

• NYHA class II-IV;
• LVEF <=35%;
• LBBB with QRS duration >=130ms.

Exclusion Criteria:

• moderate-to-severe aortic stenosis;
• frequent premature ventricular complexes;
• significant peripheral vascular disease.