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Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.
A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter.
after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis.
Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with iatrogenic PUJO | Experimental | patients with iatrogenic PUJO or long segment ureteric stricture disease for safety and efficacy of using buccal graft for repair |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| buccal mucosal graft to repair iatrogenic PUJO | Procedure | Augmented buccal mucosal graft anastomosis to repair iatrogenic PUJO or long segment ureteric stricture disease |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with patent renal pelvis and ureter after surgery. | 3 months after surgery Diuretic renography will be done to judge patency of the pelvis and ureter and resolution of hydronephrosis | 3 months |
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Inclusion Criteria:
- any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture
Exclusion Criteria:
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study protocol statistical analysis results
June 2021
through clinical trials webpage
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| ID | Term |
|---|---|
| C537373 | Multicystic renal dysplasia, bilateral |
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20 patients with iatrogenic pelviureteric junction obstruction or ureteric stricture disease
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