Role of Suppression of Endometriosis With Progestins Before IVF-ET

Role of Suppression of Endometriosis With Progestins Before IVF-ET: a Non-inferiority Randomized Controlled Trial

This study aimed to assess the role of Dienogest pretreatment for endometriosis suppression as compared to Gonadotropin-releasing hormone agonist (GnRHa) in patients with endometriosis pursuing IVF treatment.

Inclusion Criteria:

• confirmed diagnosis of endometriosis
• body mass index < 35 Kg/m2

Exclusion Criteria:

• if they have been already on long-term down-regulation of the pituitary gland with GnRHa for control of endometriosis
• liver or kidney disease
• evidence of diminished ovarian reserve (e.g. high FSH level >12 IU/L or low AMH level <1 ng/ml).