A randomized placebo controlled trial to determine if increased dietary fiber will prevent weight gain, inhibit adiposity and reduce perceived stress levels in residents at the Waco Family Health Center as the result of changes in distal gut microbiota composition and function.

This study will utilize a single blind, placebo controlled, parallel design to assess the effect of dietary fiber [Prebiotin] on the gut microbiome, perceived stress, anthropometric variables, and clinical biomarkers of metabolism. All participants in this study will be resident physicians at the Family Health Center in Waco, TX. This population was selected based on pilot data indicating they are at a greater risk for weight gain and have higher levels of stress than the average population. The goal is to recruit 40 participants for a 12 week intervention trial.

Inclusion Criteria:

• Currently a resident in training at the Family Health Center in their first year.

Exclusion Criteria:

• Pregnancy
• Currently on prescribed metformin or NSAIDS
• A diagnosed gastro-intestinal disease (i.e. irritable bowel syndrome or Crohn's disease)
• Known allergy to the supplement, placebo, or provided meal replacements
• Antibiotic use within the last 3 months.

No plan to share individual data