efficacy and safety of Sofosbuvir containing regimens in treatment of COVID-19 Egyptian patients,

The study aims to assess Sofosbuvir containing regimens in treatment of COVID-19 Egyptian patients,

Inclusion Criteria:

• COVID 19 positive patients

Exclusion Criteria:

• COVID-19 patients with critical manifestations.
• Sepsis.
• Acute respiratory distress syndrome (ARDS).
• Decompensated liver disease (Child-Pugh class B or C disease).
• Chronic renal impairment.
• Patients with blood diseases (severe anemia, thalassemia, ITP, leukemia ….).
• Ischemic heart disease within the last 6 months.
• Chronic pulmonary disease.
• Malignancy.
• Pregnancy or breastfeeding.
• Hypersensitivity to sofosbuvir or ribavirin.
• Patients with organ transplant.
• Unwilling to participate in our study