Upadacitinib Treatment Patterns, Achievement of Treatment Targets and Maintenance of Response in Moderate to Severe Rheumatoid Arthritis Patients in Real-World Practice (UPHOLD)
Upadacitinib Treatment Patterns, Achievement of Treatment Targets and Maintenance of Response in Moderate to Severe Rheumatoid Arthritis Patients in Real-World Practice (UPHOLD)
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the treatment patterns, achievement of treatment targets and maintenance of response.
Upadacitinib is a drug approved for the treatment of moderately to severely active rheumatoid arthritis. Adult participants with moderate to severe RA who have been prescribed upadacitinib by their physicians will be enrolled. Approximately, 1660 participants will be enrolled this study, worldwide.
Participants will not receive Upadacitinib as part of this study, but will be followed for response to treatment for up to 24 months.
There may be higher burden for participants in this trial compared to their standard of care. Participants will attend regular visits, every 3 months, during the course of the study at a hospital or clinic and will be asked to provide additional information by questionnaire at each visit.
Inclusion Criteria:
Exclusion Criteria:
- Prior treatment with Upadacitinib.
Ciudad Autonoma de Buenos Aire, Buenos Aires F.D. 1015, Argentina
Ciudad Autonoma de Buenos Aire, Buenos Aires F.D. 1055, Argentina
San Miguel de Tucumán, Tucumán Province 4000, Argentina
Les Abrets En Dauphine, Isere 38490, France
Roanne, Pays de la Loire Region 42300, France
Monaco, 98000, France
Saint-Priest-en-Jarez, 42270, France
Elm Park, Dublin D04 T6F4, Ireland
Torette, Ancona 60020, Italy
Cona, Ferrara 44124, Italy
Rome, Lazio 00168, Italy
Alessandria, 15100, Italy
Bergamo, 24127, Italy
Salerno, 84131, Italy
Siena, 53100, Italy
Udine, 33100, Italy
Guadalajara, Jalisco 44650, Mexico
Guadalajara, Jalisco 44690, Mexico
Mexico City, Mexico City 11850, Mexico
Mexico City, 11650, Mexico
Moscow, Moscow Oblast 129110, Russia
Samara, Samara Oblast 443095, Russia
Saint Petersburg, Sankt-Peterburg 193015, Russia
Khanty-Mansyisk, 628011, Russia
Surgut, 628400, Russia
Mushait, 61961, Saudi Arabia
San Cristóbal de La Laguna, Santa Cruz De Tenerife 38320, Spain
Basel Town, Canton of Basel-City 4031, Switzerland
Lausanne, Canton of Vaud 1011, Switzerland
Taipei City, Taipei 100, Taiwan
Dubai, United Arab Emirates