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| Name | Class |
|---|---|
| Herlev and Gentofte Hospital | OTHER |
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The purpose of the study is to compare the effect of whey protein and collagen on fat free mass, muscle strength, functional ability, wound healing and life quality in elderly patients undergoing elective knee- or hip surgery (defined as elective knee- or hip arthroplasty). The patients are admitted at the department of Orthopaedic Surgery at Herlev Gentofte Hospital.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Collagen | Experimental | Participants of this arm are going to consume 30 g of collagen peptides daily for 30 days |
|
| Whey Protein | Experimental | Participants of this arm are going to consume 30 g of whey protein daily for 30 days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Whey protein and Collagen supplementation | Dietary Supplement | Participants of each arm will consume 30 g daily of the assigned protein supplementation for 30 days. The protein supplementation will be given as protein powder which the participants will have to dissolve in cold drinks. During the intervention fat free mass, muscle strength, functional ability, wound healing and life quality of the participants will be monitored. |
| Measure | Description | Time Frame |
|---|---|---|
| The difference in fat free mass | The outcome will be monitored through BIA and the development of fat free mass in the operated leg will be compared to the development of fat free mass in the non-operated leg. | Weekly for 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Wound healing | The amount of days until the wound is healed (defined as: the epithelium is covered without crust). This will be monitored trough pictures and assessed on a scale from 1-5 by a masked doctor. | Weekly for 30 days |
| Redness and infection |
| Measure | Description | Time Frame |
|---|---|---|
| Palatability of the protein supplementation | Assessed on a scale from 1-5 | 30 days |
| Consistency of the protein supplementation | Assessed on a scale from 1-5 |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Herlev/Gentofte Hospital | Gentofte Municipality | Hellerup | 2900 | Denmark |
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| ID | Term |
|---|---|
| D055948 | Sarcopenia |
| ID | Term |
|---|---|
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D000067816 | Whey Proteins |
| ID | Term |
|---|---|
| D008894 | Milk Proteins |
| D000080224 | Animal Proteins, Dietary |
| D004044 | Dietary Proteins |
| D011506 | Proteins |
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|
The redness and infection around the wound assessed on a scale from 1-5 by a masked doctor through pictures.
| Weekly for 30 days |
| Handgrip strength | Handgrip strength measured by a handdynanometer (SAEHAN) in kg and percentage | Weekly for 30 days |
| Extension strength of quadriceps femoris | Measured in amounts of repetitions of 0.5 or 1.0 kg. | Weekly for 30 days |
| Life quality | Measured trough EuroQol-5D-5L | Weekly for 30 days |
| Difference in functional ability (NMS) | Assessed by New mobility score | Weekly 30 days |
| Difference in Chair stand test | Measured by amount of repetitions | Weekly for 30 days |
| 30 days |
| Compliance of the protein supplementation intake | Assessed trough a weekly form, which the participants will fill in | Weekly for 30 days |
| Rapported side effects | Participants will be informed to rapport if they experience any side effects throughout the intervention | 30 days |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D000602 |
| Amino Acids, Peptides, and Proteins |
| D000067796 | Whey |
| D008892 | Milk |
| D003611 | Dairy Products |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |