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The purpose of the study was to determine the levels of Resolvin D1 (RVD1) in the gingival crevicular fluid (GCF) and saliva of the patients with periodontitis (P) and also to investigate the effects of non-surgical periodontal treatments (NSPTs) on its levels.
A total of 26 subjects (15 P, 11 healthy) were included. Clinical periodontal measurements, GCF and saliva samples were collected from each individual at baseline and 1 month after NSPTs in P group. RVD1 levels were determined by enzyme-linked immunosorbent assay (ELISA) method.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Periodontitis patients | Active Comparator | gingival crevicular fluid and saliva collection were taken before and after nonsurgical periodontal treatment |
|
| Healthy individuals | No Intervention | gingival crevicular fluid and saliva collection were taken at baseline after oral hygiene instructions |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| periodontal therapy | Procedure | Non surgical periodontal therapy was performed to patients with peridontitis |
|
| Measure | Description | Time Frame |
|---|---|---|
| Biochemical parameter (resolvin D1) | The changes in levels of resolvin D1 after periodontal treatment determined by ELISA. | Baseline and 1 month after NSPT |
| Measure | Description | Time Frame |
|---|---|---|
| Probing pocket depth | The changes in probing pocket depth after periodontal treatment were evaluated | Baseline and 1 month after NSPT |
| Clinical attachment level (CAL) | The changes in CAL after periodontal treatment were evaluated |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ordu University | Ordu | 52200 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| Baseline and 1 month after NSPT |
| Plaque index (PI) | The changes in PI after periodontal treatment were evaluated | Baseline and 1 month after NSPT |
| Gingival index (GI) | The changes in GI after periodontal treatment were evaluated | Baseline and 1 month after NSPT |