Treatment Rates and Compliance to Treatment in Patients With Familial Hypercholesterolemia

Awareness, Treatment Rates and Compliance to Treatment in Patients With Serum LDL Cholesterol Higher Than 250 mg/dL, and Possible, Probable or Definite Familial Hypercholesterolemia

Familial hypercholesterolemia is a genetic disease characterized by increased levels of low density lipoprotein cholesterol (LDL-C). It is underdiagnosed and undertreated despite relatively high prevalence and significant association with increased mortality.

Patients older than 18 years old and have a serum low density LDL-C≥250 mg/dL were identified from the hospital database. A questionnaire was completed via phone. Patients were classified as definite, probable and possible familial hypercholesterolemia according to Dutch Lipid Clinical Network Criteria

Inclusion Criteria:

• Patients older than 18 years old and have a serum LDL-C≥250 mg/dL

Exclusion Criteria:

• Patients who refuse dto interview
• Serum TSH≥10 mIU/mL
• Glomerulonephritis or nephrotic syndrome
• ALT or AST higher than 3 times of normal limits
• Serum triglyceride >400 mg/dL