Iron Therapy in Patients With End-Stage Renal Disease

A Cross-over Trial to Evaluate the Efficacy and Safety Between Increasing the Dose of Iron and Original Iron Dosage in Patients With Maintenance Hemodialysis

This study will compare the clinical outcome of patients with maintenance dialysis room after changing the iron treatment guidelines from original upper limit with ferritin>500ng/ml, or TSAT>20% to Ferritin> 800ng / ml, or TSAT> 50%.

After two years of treatments, we will compare the incidence of clinical events, monthly blood, and biochemical examination data for the two years before and after the change.

Inclusion Criteria:

• patients receiving maintenance dialysis

Exclusion Criteria:

• less than 20 year-old, oncological patients undergoing chemotherapy, abnormal liver function, infection