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A small cross-over trial on 24 people involving an herbal tea blend to test whether consuming 1 cup of tea triggers changes in the numbers of natural killer cells in the blood circulation as evidence of immune cell trafficking within 2 hours.
A randomized, cross-over, controlled study design will be used to evaluate the effects of consumption of 1 cup of an herbal tea blend to consumption of the same volume of warm water. The study is of 3 weeks' duration, with evaluation of the herbal tea blend versus warm water at week 1 and week 2 with a one week washout between visits. On each visit, a baseline blood draw is performed, followed by consuming of the herbal tea blend or warm water. Blood draws are performed at 1 and 2 hours after consumption.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Herbal tea blend | Active Comparator | 1 cup of herbal tea blend containing Rosehip and other berry extracts. |
|
| Warm water | Sham Comparator | 1 cup of warm water. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Herbal tea blend | Dietary Supplement | 1 cup of freshly brewed tea from an herbal tea blend. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change to natural killer cell numbers in blood circulation | Flow cytometry evaluation of natural killer cell numbers | Changes at 1 and 2 hours after consumption |
| Measure | Description | Time Frame |
|---|---|---|
| Change to natural killer cell activation status | Flow cytometry evaluation of CD69 expression on natural killer cells in the blood circulation | Changes at 1 and 2 hours after consumption |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| GITTE JENSEN | NIS Labs | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gitte Jensen | Klamath Falls | Oregon | 97601-5904 | United States |
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The study uses a randomized double-blinded controlled cross-over study design.
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| Warm water | Dietary Supplement | 1 cup of warm water |
|