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Glaucoma remains the leading cause of irreversible blindness worldwide. Glaucoma represents a group of diseases that lead to optic nerve damage and corresponding deterioration of the visual field.
Elevated intraocular pressure remains the most important risk factor. Interestingly, glaucomatous damage sometimes occurs despite seemingly normal intraocular pressure.
Recent studies suggest pressure peaks, which are missed under the current practice of spot intraocular measurements during office hours. In order to detect pressure peaks diurnal measurements are mandatory. Costly in-hospital diurnal measurements are the current standard.
The primary study objective is to verify that self-tonometry at home can provide valuable information when looking for pressure peaks in patients with glaucoma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| icare HOME | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| icare HOME device (Icare Oy, Vanda, Finland) | Device | icare HOME device versus hospital based measurements |
|
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of an in- hospital diurnal pressure pattern of intraocular pressure to the pattern derived from self-tonometry using icare HOME in an outpatient setting. | Statistical methods for analysis of continuous method comparison data will be applied. The primary goal is to quantify the extent of agreement between two methods (Intraocular pressure measurement in-hospital and at home) and determine whether they sufficiently agree to be used interchangeably. | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| variance of diurnal intraocular pressure | Quantitative evaluation of day to day variance of diurnal intraocular pressure measurement in an out-hospital setting in patients with open angle glaucoma, normal tension glaucoma and healthy controls | 4 years |
| Influence of daily activities |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Raphael Fritsche, MD | Contact | 0041 205 33 76 | raphael.fritsche@luks.ch |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cantonal Hospital of Lucerne | Recruiting | Lucerne | 6004 | Switzerland |
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| ID | Term |
|---|---|
| D005901 | Glaucoma |
| ID | Term |
|---|---|
| D009798 | Ocular Hypertension |
| D005128 | Eye Diseases |
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Influence of daily activities (sports, alcohol and water intake) on intraocular measurements at home (questionnaire) |
| 4 years |
| Change of treatment | Change of treatment due to intraocular pressure peaks during hospitalisation and/or measurements at home | 4 years |