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Papaya has effects on oral pathogenic microorganisms, it also has anticoagulant quality, amebicidal action, antimicrobial, bacteriostatic and antifungal activity on different bacteria, especially on Streptococcus mutans, this can be exploited in the dental area. The objective of the study was to determine the efficacy of Carica Papaya peel extract (suckling) as an inhibitor of Streptococcus Mutans in students of the dental faculty of the National University of Caaguazú in 2018.
Specific objectives
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Carica Papaya extract | Experimental | Carica Papaya at 3% |
|
| Chlorhexidine | Active Comparator | 0.12% chlorhexidine mouthwash formulation (commercially available) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CARICA PAPAYA MOUTHWASH | Other | Each application was 10 ml. applied for 1 minute, once a day for 8 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of Colony Forming units (Stage 1) | Before Intervention | thorough study completion, an average of 24 hours |
| Number of Colony Forming units (Stage 2) | After Intervention | 10 minutes after mouthwash use |
| Number of Colony Forming units (Stage 3) | After Intervention | 8 days after mouthwash use |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Diego Céspedes | Facultad de OdontologÃa, Universidad Nacional de Caaguazu | Principal Investigator |
| Ulises A Villasanti Torales | Facultad de Odontologia, Universidad Nacional de Caaguazu | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Facultad de OdontologÃa Universidad Nacional de Caaguazú | Coronel Oviedo | International | 595 | Paraguay |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30486374 | Background | Saliasi I, Llodra JC, Bravo M, Tramini P, Dussart C, Viennot S, Carrouel F. Effect of a Toothpaste/Mouthwash Containing Carica papaya Leaf Extract on Interdental Gingival Bleeding: A Randomized Controlled Trial. Int J Environ Res Public Health. 2018 Nov 27;15(12):2660. doi: 10.3390/ijerph15122660. |
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By email
From the time the protocol is available in clinical trials.gov and with no limit of time
Researchers that want to know about the study and use the protocol
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| ID | Term |
|---|---|
| D003773 | Dental Plaque |
| ID | Term |
|---|---|
| D003741 | Dental Deposits |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| CHLORHEXIDINE MOUTHWASH | Other | Each application was 10 ml. applied for 1 minute, once a day for 8 days |
|