Low-Level Laser in Head and Neck Chronic Lymphedema

Low-level Laser in Treatment of Head and Neck Chronic Lymphedema: A Pilot Randomized Controlled Trial

The purpose of this study is to evaluate the effect of low-level laser treatment (LLLT) on the severity of lymphedema, symptom burden, functional status, and quality of life in HNC survivors.

Primary aim: To determine the impact of LLLT, as compared to wait-list control, on changes in severity of lymphedema.

Secondary aim: To determine the impact of LLLT, as compared to a wait-list control, on lymphedema-related symptom burden (e.g., tightness), functional impairments (e.g., range of motion in jaw and neck), and quality of life.

Inclusion Criteria:

• >18 years of age
• >6 months post HNC treatment
• No evidence of cancer confirmed with imaging tests
• Having head and neck lymphedema with or without fibrosis
• Completion of initial lymphedema therapy
• Lymphedema duration between 3-24 months
• Ability to speak and read English
• Ability to provide informed consent

Exclusion Criteria:

Patients will be excluded if they have any of the following medical conditions that would prohibit the safe implementation of LLLT:

• Pregnancy
• Acute infection
• Photosensitivity
• Chronic inflammatory diseases
• Venous thrombosis
• Carotid artery stenosis
• History of severe trauma
• Medication that affects body fluid and electrolyte balance
• Use of high doses of non-steroidal anti-inflammatory drugs
• Pre-existing skin rash, ulceration, open wound in the treatment area
• Active lymphedema therapy or physical therapy
• Allergic and other systemic skin diseases