The purpose of the pediatric liver transplant biobank is to systematically collect clinical specimens from pediatric end-stage liver disease. It is expected to contribute to the research and development of paediatric end-stage liver disease in the future.

Inclusion Criteria:

1. Children diagnosed with end-stage liver disease.
2. Liver transplantation in our hospital.
3. informed patient consent.
4. long-term follow-up in our hospital.

Exclusion Criteria:

No fixed contact information, difficult to follow up the patients.

Children with end-stage liver disease who undergo liver transplantation in our hospital. Obtain their or their parents' informed consent before the project starts.