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| Name | Class |
|---|---|
| University Hospitals, Leicester | OTHER |
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants randomised to 1.5T then 3T | Participants randomized to be scanned at 1.5T first followed by 3T |
| |
| Participants randomised to 3T then 1.5T | Participants randomized to be scanned at 3T first followed by 1.5T |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiovascular Magnetic Resonance (CMR) imaging at 1.5T | Diagnostic Test | Long and short axis bSSFP cines images, long and short axis tagging images and aortic cine images will be obtained. Participants will be randomised to either have cine or tagging images obtained first. |
| Measure | Description | Time Frame |
|---|---|---|
| Inter-field strength agreement of left ventricular global longitudinal strain (GLS) | The inter-field strength agreement of left ventricular global longitudinal strain (GLS) measured using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Inter-field strength agreement of left ventricular global circumferential strain (GCS) | The inter-field strength agreement of left ventricular global circumferential strain (GCS) measured using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of left ventricular short- and long-axis global radial strain (GRS) |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy volunteers, male and female, aged 18 years or above
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Leicester | Leicester | United Kingdom |
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| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
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| Cardiovascular Magnetic Resonance (CMR) imaging at 3T | Diagnostic Test | Long and short axis bSSFP cines images, long and short axis tagging images and aortic cine images will be obtained. Participants will be randomised to either have cine or tagging images obtained first. |
|
The inter-field strength agreement of left ventricular short- and long-axis global radial strain (GRS) measured using cvi42 Tissue Tracking at 1.5T and 3T |
| Day 1 |
| Inter-field strength agreement of left ventricular longitudinal peak early diastolic strain rate (long. PEDSR) | The inter-field strength agreement of left ventricular longitudinal peak early diastolic strain rate (long. PEDSR) measured using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of left ventricular circumferential peak early diastolic strain rate (circum. PEDSR) | The inter-field strength agreement of left ventricular circumferential peak early diastolic strain rate (circum. PEDSR) measured using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of left ventricular radial peak early diastolic strain rate (rad. PEDSR) | The inter-field strength agreement of left ventricular radial peak early diastolic strain rate (rad. PEDSR) measured using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of left ventricular peak torsion | The inter-field strength agreement of left ventricular peak torsion measured using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Inter-vendor agreement of left ventricular systolic and diastolic strain measurements at 1.5T and 3T | The inter-vendor agreement of left ventricular systolic and diastolic strain measurements with different software packages (TomTec, QMass, cvi42) using cine-based imaging at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of left ventricular systolic and diastolic strain measurements using cine-based imaging and tissue tagging techniques | The inter-field strength agreement of left ventricular systolic and diastolic strain measurements derived using cine-based imaging and tissue tagging techniques at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of left and right atrial and ventricular volumes and function | The inter-field strength agreement of left and right atrial and ventricular volumes and function at 1.5T and 3T | Day 1 |
| Inter- and intra-observer variability of left ventricular systolic and diastolic strain measurements | The inter- and intra-observer variability of left ventricular systolic and diastolic strain measurements using cvi42 Tissue Tracking at 1.5T and 3T | Day 1 |
| Inter-field strength agreement of aortic strain | The inter-field strength agreement of aortic strain measured at 1.5T and 3T | Day 1 |