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| ID | Type | Description | Link |
|---|---|---|---|
| 2019-A02328-49 | Other Identifier | ID RCB |
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team no more available to lead research
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The term perceptual awareness refers to subjective experience... or the phenomenology associated with the processing of a sensory stimulus. The term metacognition refers to our ability of introspection, knowledge and control of our own cognitive processes. The objective of this research is to establish the contribution of the basal ganglia and thalamus to the perceptual awareness and meta-cognition, using deep brain stimulation coupled with electroencephalography.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Parkinson disease |
| ||
| essential tremor |
| ||
| dystonia |
| ||
| OCD |
| ||
| healthy volunteers |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| deep brain stimulation | Device | Behavioral and electroencephalographic responses will be compared on and off deep brain stimulation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Behavioral effect of DBS on confidence | Confidence in correct and incorrect responses will be compared on and off stimulation | by fall 2024 |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of DBS on EEG markers of confidence | EEG correlates of confidence in correct and incorrect responses will be compared on and off stimulation | by fall 2024 |
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Inclusion Criteria:
Exclusion Criteria:
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Pathologies included will be Parkinson's disease (PD), essential tremor, dystonia, and obsessive compulsive disorder (OCD).
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| Name | Affiliation | Role |
|---|---|---|
| ELENA MORO | University Hospital, Grenoble | Principal Investigator |
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Experimental paradigms, anonymized behavioral and EEG data and analysis scripts will be made freely available on dedicated platforms (e.g zenodo)
Data will be shared upon publication of results, for an unlimited duration.
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| D004421 | Dystonia |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D046690 | Deep Brain Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D013514 | Surgical Procedures, Operative |
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| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |