Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Pain Control in Modified Radical Mastectomy

Comparison of Efficacy of Ultrasound-guided Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Intra and Postoperative Pain Control in Modified Radical Mastectomy: a Randomized Controlled Trial.

The aim of the study is to compare the effectiveness of the Erector spinae plane (ESP) block versus thoracic paravertebral (TPV) block in the post-operative pain control after radical mastectomy.

Primary outcome of our study is to compare the effectiveness of two regional anesthesia techniques, ESP block and TPV block, in the post-operative pain-control after radical mastectomy.

We will also evaluate both intra and post-operative opioid consumption, the incidence of PONV, the length of hospital stay, patient satisfaction with the anesthesiology technique and the incidence of chronic pain 6 months after surgery.

Inclusion Criteria:

• Patients aged between 18 and 85
• American Society of Anesthesiologists classification I - III
• Signature of consent to participate in the study

Exclusion Criteria:

• Coagulopathies and / or use of antiplatelet / anticoagulant drugs
• Infections and/or lesions at the puncture site,
• BMI ≥40
• allergies and / or contraindications to the administration of the drugs used in the study,
• use of chronic opioid therapy