Comprehensive Assessment of Risks for Miscarriage.

Markers of Ultrasound, Immunologic & Serum Factors in the Comprehensive Analysis of Risks for Early Pregnancy Loss.

This study aims to determine the role of serum biomarkers and placental bloodflow in the comprehensive evaluation of the risk for spontaneous abortion

To study the added value (if any) of combining serum markers, immunologic factors, and ultrasound parameters in comprehensively evaluating the risk for spontaneous abortion.

Inclusion Criteria:

• visualized fetal structures in utero & heart pulsations until 8th week of gestation
• normal THS/T4 levels
• no uterine malformations
• BMI < 27
• signed informed consent

Exclusion Criteria:

• fetal structures in utero & heart pulsations not visualized until the 8th week of gestation
• elevated THS/T4 levels
• uterine malformations
• BMI > 27