To report on cases presented with combined endophthalmitis and orbital cellulitis as a first presentation of covid-19 infection.

This observation case series study included 5 patients referred to the Ophthalmology Department, Minia University with severe ophthalmic manifestations in the form of combined endophthalmitis and orbital cellulitis. On doing the work-up of covid-19 infection according to the recommendations of Egyptian Ministry of Health, patients proved to be infected by the novel Corona virus. In addition to the Corona work-up, all patients were subjected to full ophthalmological evaluation, ocular ultrasound and orbital CT examination.

Inclusion Criteria:

• Patients with endophthalmitis and orbital cellulitis with covid-19

Exclusion Criteria:

• Patients without endophthalmitis and orbital cellulitis.
• Patients with endophthalmitis and orbital cellulitis not having covid-19 infection.

5 patients referred to the Ophthalmology Department, Minia University with severe ophthalmic manifestations in the form of combined endophthalmitis and orbital cellulitis. On doing the work-up of covid-19 infection according to the recommendations of Egyptian Ministry of Health, patients proved to be infected by the novel Corona virus.