Hormonal and Metabolic Aspects of Endoscopic Sleeve Gastroplasty

Hormonal and Metabolic Aspects of Endoscopic Sleeve Gastroplasty

The investigators of the study want to investigate the complex interactions between glucose metabolism, food intake/weight loss, and different appetite regulating hormones after ESG in comparison with conventional laparoscopic sleeve gastrectomy (LSG).

Inclusion Criteria:

• Age > 18 years
• Scheduled for endoscopic or laparoscopic sleeve at Hvidovre Hospital
• HbA1c < 48 mmol/mol before surgery, and no history of diabetes
• HbA1c < 48 mmol/mol and fasting plasma glucose < 6.1 mmol/l at inclusion
• BMI<45

Exclusion Criteria:

• Hemoglobin < 6.5 mmol/l at inclusion
• Pregnancy or breast feeding
• Medication affecting the planned examinations