Artificial Induction of Labour in Full-term Singleton Pregnancy : Comparative Randomized Trial of Two Strategies

Artificial Induction of Labour in Full-term Singleton Pregnancy : Comparative Randomized Clinical Trial of Two Strategies (DINO-FIRST Versus BALLON-FIRST)

Labour induction is an obstetrical procedure, which artificially starts the process of cervix dilation, in order to induce labour. Several methods of labour induction exist : mechanical ones (using dilatation balloons) or pharmacological ones (using prostaglandins or oxytocin). This trial aims to compare, in case of non-favourable cervix, the strategy of labour induction using the Propess® method first (Dino-first) versus the strategy beginning with the use of a dilatation balloon (Ballon-first), with respect of the usual practice and the current guidelines.

Inclusion Criteria:

• Women with singleton pregnancy
• Fetus with cephalic presentation
• Intact membranes between 37 and 42 weeks of amenorrhea
• Medical indication for labour induction according to the "Haute Autorité de Santé" (HAS) guidelines
• Unfavourable cervix (Bishop scoring < 7)
• Age > 18 years-old
• Person affiliated to a healthcare system
• Good understanding of the French language

Exclusion Criteria:

• Previous C-section or uterine incision
• Placenta previa
• Metrorrhagia of unknown origin
• Lethal foetal abnormality
• Hyperreactivity to one of the molecules used for the induction (dinoprostone or oxytocin) or to latex
• Subject participants to another biomedical research
• Subject under legal guardianship or curatorship