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Pectus carinatum is a deformation of the thoracic wall causing an aesthetic prejudice. Since 2011, our team uses a dynamic compression system to treat this deformation. It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it. The local cohort is one of the largest in the world. The few previous publications have shown the validity of this method, but the prognosis factors for success of this innovative treatment are not yet identified.
The principal insvestigator hypothesizes that the success or failure of the treatment depends on several parameters assessable before treatment, such as the patient's age, gender, initial correction pressure, symmetry or not of the deformation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Retrospective cohort | 340 to 400 patients |
| |
| Validation cohort | 120 patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| dynamic compression system | Other | It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it |
| Measure | Description | Time Frame |
|---|---|---|
| Decrease of the deformation of more than 50% (measured in mm) after 6 months of treatment | Dynamic compression system | After 6 months of treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Failure of treatment assessed by the patient, ie if the patients considers the treatment to have failed, if he choose to underwent surgery afterwards, or if he considered the pectus carinatum to have relapsed | Dynamic compression system | After the end of treatment (6 months to 2 years) |
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Inclusion Criteria:
Exclusion Criteria:
-
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Refusal to participate to this treatment
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Aurélien SCALABRE | Contact | 04 77 82 94 49 | aurelien.scalabre@chu-etienne.fr |
| Name | Affiliation | Role |
|---|---|---|
| Aurélien SCALABRE | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Saint-Etienne | Recruiting | Saint-Etienne | 42055 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41390917 | Derived | Kieffer De Marco L, Filaire L, Vermersch S, Chapelle C, Garcin A, Tiffet O, Scalabre A. Prognostic Factors for Pectus Carinatum Treated by Dynamic Compression System: PECTUSDYN Trial. Eur J Cardiothorac Surg. 2026 Jan 6;68(1):ezaf444. doi: 10.1093/ejcts/ezaf444. |
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| ID | Term |
|---|---|
| D066166 | Pectus Carinatum |
| ID | Term |
|---|---|
| D001848 | Bone Diseases, Developmental |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D002357 | Cartilage Diseases |
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| D009139 |
| Musculoskeletal Abnormalities |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |