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| ID | Type | Description | Link |
|---|---|---|---|
| 2019-A01673-54 | Other Identifier | ANSM |
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lack of inclusion
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Two movement illusion techniques can currently be used in clinical practice for motor rehabilitation after stroke hemiplegia: visual illusion (mirror therapy) and proprioceptive illusion (tendon vibration). Mirror therapy, in its computerized version (IVS3, Dessintey, Saint-Etienne, France), is based on the substitution of the deficient visual feedback by a visual feedback of a correctly realized movement. The proprioceptive illusion is based on the external application of a vibrator on muscle tendons at a frequency between 50 and 120 Hz. These two techniques are currently used independently. They are, in theory, complementary and additive. No study has described the combinatorial properties of the illusions generated by these 2 techniques in hemiplegic subjects and healthy subjects.
The study hypothesis is that the administration of mirror therapy together with vibration will increase the perception of movement in a subjective scale.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient with first stroke causing hemiplegic | Experimental | Patient with first stroke causing hemiplegic will be included. They will have Computerized Mirror Therapy (CMT) associated at tendon vibration:
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| healthy subjects | Sham Comparator | Healthy subjects will be included. They will have Computerized Mirror Therapy (CMT) associated at tendon vibration:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computerized Mirror Therapy (CMT) | Device | Computerized Mirror Therapy (CMT) will be realizing by the device Intensive Visual Simulation 3 (IVS3). The patient looks on a screen in front of him, mirroring the movements made by his hand, while attempting to perform the same movement with his other hand. |
| Measure | Description | Time Frame |
|---|---|---|
| subjective measure of the intensity of the perception of movements: change from baseline impression of movement at day 7 | Measured impression of movement on conditions (visual and/or proprioceptive; yes/no/don't know) | Day: 0, 7 |
| subjective measure of the intensity of the perception of movements: change from baseline nature of this impression at day 7 | Measured nature of this impression of movement (flexion/extension) | Day: 0, 7 |
| subjective measure of the intensity of the perception of movements: change from baseline intensity of the movement felt at day 7 | Measured intensity of the movement felt by Visual Analogue Scale (VAS) results (0 = no sense of movement and 10 = like real movement.) | Day: 0, 7 |
| Measure | Description | Time Frame |
|---|---|---|
| Objective measurement of the perceived movement angle reproduced without motor intention by the hemiplegic subjects with the healthy limb | Measured by Kinovea software. | Day: 0, 7 |
| Measurement of motor intention in hemiplegic subjects by experimental conditions |
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Inclusion Criteria:
Hemiplegic subjects :
Healthy subjects :
Exclusion Criteria:
Hemiplegic subjects :
Healthy subjects :
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| Name | Affiliation | Role |
|---|---|---|
| Pascal GIRAUX, PhD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Saint-Etienne | Saint-Etienne | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39267092 | Derived | Adham A, Bessaguet H, Struber L, Rimaud D, Ojardias E, Giraux P. Distinct and additive effects of visual and vibratory feedback for motor rehabilitation: an EEG study in healthy subjects. J Neuroeng Rehabil. 2024 Sep 12;21(1):158. doi: 10.1186/s12984-024-01453-3. |
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| ID | Term |
|---|---|
| D006429 | Hemiplegia |
| D020521 | Stroke |
| ID | Term |
|---|---|
| D010243 | Paralysis |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| Tendon vibration | Device | Transcutaneous vibrations are used. This device allows vibrations from 50 to 120 Hz with amplitude of 1 mm. This study the frequency used is 70 and 80 Hz. |
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Measured by Visual Analogue Scale (VAS) results (0 = no sense of movement and 10 = like real movement). |
| Day: 0, 7 |
| To compare the Visual Analogue Scale (VAS) score according to the level of motor impairment | Level of motor impairment is measured by Medical Research Council (MRC) score. Medical Research Council (MRC) score evaluate motricity (0= paralyzed). | Day: 0 |
| To compare the Visual Analogue Scale (VAS) score with the Erasmus modified Nottingham Sensory Assessment (EmNSA) score | Erasmus modified Nottingham Sensory Assessment (EmNSA) score evaluated the level of sensory impairment. The Erasmus modified Nottingham Sensory Assessment (EmNSA) includes 2 subscales: somatosensory score (min 0 and max 44) and stereognosis (min 0 and max 20) for left and right members. | Day: 0 |
| Intensity of the perception of movements using a visual analogue scale and the objective measurement of perceived movement angle reproduced by the healthy subjects with the vibrated arm | Measured by Kinovea software. | Day: 0, 7 |
| Brain activity according to different experimental conditions (with and without vibration or with and without visual illusion) in hemiplegic subjects. | Multi Channel EEG Acquisition System | Day: 0, 7 |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |