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Prospective observational trial in patients admitted to ICU diagnosed with COVID-19 requiring invasive mechanical ventilation. Characterization of Reverse Triggering asynchrony during the first 5 days of invasive mechanical ventilation and other asynchronies, and its correlation with different outcomes.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Asynchronies detection | Diagnostic Test | Asycnhronies detection |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence and pattern of presentation of Reverse triggering in COVID-19 patients under invasive mechanical ventilation | To analyze the incidence of Reverse Triggering in the initial phases of invasive mechanical ventilation in COVID-19 patients | during the 5 first days of invasive mechanical ventilation |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of Reverse Triggering related to the level of sedation in COVID-19 patients under invasive mechanical ventilation | To correlate the presence of Reverse Triggering with the level of sedation and use of neuromuscular blockers | From the day of mechanical ventilation initation up to 5 days or the last day of mechanical ventilation |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients admitted to the ICU under invasive mechanical ventilation with ARDS secondary to COVID-19
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Candelaria de Haro | Sabadell | Barcelona | 08208 | Spain |
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| Reverse triggering and secondary asynchronies in COVID-19 patients under invasive mechanical ventilation |
To analyze the incidence of breath stacking and ineffective efforts secondary to RT. |
| From the day of mechanical ventilation initiation up to 5 days |
| Incidence and pattern of presentation of asynchronies in COVID-19 patients under invasive mechanical ventilation | To analyze the incidence of RT, ineffective efforts and double triggering throughout the period of invasive mechanical ventilation | Each day from the day of mechanical ventilation initiation until the day of mechanical ventilation withdrawal or up to 28 days |
| Influence of asynchronies in different outcomes in in COVID-19 patients under invasive mechanical ventilation | To correlate the presence of asycnhronies and its type with duration of invasive mechanical ventilation, ICU length of stay and survival | Each day from the day of mechanical ventilation initiation until the end of invasive mechanical ventilation, ICU discharge and hospital discharge or up to 28 days |