A Randomised, Double-blind, Parallel-group, Active Controlled Study Evaluating the Efficacy of Vortioxetine Versus Desvenlafaxine in Adult Patients Suffering From Major Depressive Disorder With Partial Response to SSRI Treatment
A Randomised, Double-blind, Parallel-group, Active Controlled Study Evaluating the Efficacy of Vortioxetine Versus Desvenlafaxine in Adult Patients Suffering From Major Depressive Disorder With Partial Response to SSRI Treatment
The purpose of this study is to compare the efficacy of vortioxetine versus desvenlafaxine after 8 weeks of treatment in patients that have tried one available treatment without getting the full benefit
The study will consist of a screening period of up to 14 days before the Baseline Visit, followed by an 8-week Treatment Period with vortioxetine or desvenlafaxine. A Safety Follow-up Visit will be performed approximately 4 weeks after the Primary Outcome/Withdrawal Visit.
At Baseline, patients will be equally randomised (1:1) to 1 of the 2 treatment groups for an 8-week, double-blind Treatment Period.
Inclusion Criteria:
Exclusion Criteria:
Other in- and exclusion criteria may apply
Ciudad Autonoma de Buenos Aires, Buenos Aires C1058AAJ, Argentina
Ciudad Autonoma de Buenos Aires, Buenos Aires C1133AAH, Argentina
Ciudad Autonoma de Buenos Aires, Buenos Aires C1405BOA, Argentina
Rosario, Santa Fe Province 2000, Argentina
Stavropol Region, Kochubeev District 357034, Russia
Moscow, 125284, Russia
Nizhny Novgorod, 603155, Russia
Smolensk, 214019, Russia
Vranov Nad Topou, 09301, Slovakia
Smila, Cherkasy Oblast 20708, Ukraine
Kharkiv, Kharkivska 61068, Ukraine
Kominternivskyy, Odesa Oblast 67513, Ukraine
Kharkiv, 61068, Ukraine
Lviv, 79021, Ukraine
Poltava, 36006, Ukraine