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we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19.
we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19. As, zinc may be of value in these cases and may be of value in enhancing chloroquine effect.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chloroquine or hydroxychloroquine | Experimental | Chloroquine or hydroxychloroquine alone |
|
| Chloroquine or hydroxychloroquine with zinc | Experimental | Chloroquine or hydroxychloroquine with zinc |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chloroquine or hydroxychloroquine | Drug | Chloroquine or hydroxychloroquine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients with improvement or mortality | The number of patients with improvement or mortality. | 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| sherief Abd-Elsalam, Ass. Prof. | ass. Prof. Tropical Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tanta university hospital, Assuit University, Ainshams University | Tanta | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33247380 | Derived | Abd-Elsalam S, Soliman S, Esmail ES, Khalaf M, Mostafa EF, Medhat MA, Ahmed OA, El Ghafar MSA, Alboraie M, Hassany SM. Do Zinc Supplements Enhance the Clinical Efficacy of Hydroxychloroquine?: a Randomized, Multicenter Trial. Biol Trace Elem Res. 2021 Oct;199(10):3642-3646. doi: 10.1007/s12011-020-02512-1. Epub 2020 Nov 27. |
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| ID | Term |
|---|---|
| D002738 | Chloroquine |
| D006886 | Hydroxychloroquine |
| D015032 | Zinc |
| ID | Term |
|---|---|
| D000634 | Aminoquinolines |
| D011804 | Quinolines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
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|
| zinc | Drug | Zinc tablets |
|
| D006571 | Heterocyclic Compounds |
| D019216 | Metals, Heavy |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D028561 | Transition Elements |
| D008670 | Metals |