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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A00738-31 | Other Identifier | ID-RCB number,ANSM |
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Patients with early-stage squamous cell carcinomas of the vocal cord can be treated in an equivalent way in terms of carcinology by surgery or radiotherapy. The study will be to analyse the vocal outcome at 5 years of these two types of management in order to define whether one is superior to the other on this criterion of voice quality after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgery | |||
| Radiotherapy |
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| Measure | Description | Time Frame |
|---|---|---|
| Voice Handicap Index | The VHI is a self-administered questionnaire that provides a score ranging from 0 to 120 points validated in France and internationally based on the declarative answers to 30 items of the questionnaire. A high score corresponds to a voice felt to be of poor quality. This is a subjective assessment made by the patient. | At 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum Phonation Time | The TMP is the measurement in seconds of a vowel (/a/) held for as long as possible. | At 5 years |
| Grade, Roughness, Breathiness, Asthenia, Strain, Instability SCORE (GRBASI Score) |
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Inclusion Criteria:
Exclusion Criteria:
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patients treated for glottic squamous cell carcinoma at Lille University Hospital and the Oscar Lambret Centre between 2015 and 2017.
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| Name | Affiliation | Role |
|---|---|---|
| François Mouawad, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Oscar Lambret | Lille | 59000 | France | |||
| Hôpital Huriez, CHU |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39122636 | Result | Louison J, Labreuche J, Liem X, Rysman B, Morisse M, Mortuaire G, Mouawad F. Voice quality after surgery or radiotherapy for glottic T1 squamous cell carcinoma: Results of the VOQUAL study. Cancer Radiother. 2024 Aug;28(4):373-379. doi: 10.1016/j.canrad.2024.03.004. Epub 2024 Aug 9. |
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This score is obtained from an internationally and nationally validated hetero-assessment. It consists in the attribution by a listening jury made up of two people of a mark ranging from 0 to 3 for each of the 6 items: Grade, Roughness, Breathiness, Asthenia, Strain, Instability.
A high score is associated with a voice perceived as bad by the audience.
| At 5 years |
| Acoustic Analysis by Vocalab software | short recording of the patient's voice delivering a standardized speech on VOCALAB software validated by the scientific community. | At 5 years |
| Lille |
| France |