In Highly Active Antiretroviral Therapy era, fatty liver has become an important cause of liver function damage in people living with HIV (PLWH). There are a large number of PLWH in China who are infected with hepatitis B virus and hepatitis C virus. HIV, hepatitis B virus, hepatitis C virus, drugs, alcohol, etc. affect each other, which makes the cause, diagnosis, and treatment of liver function damage in PLWH complicated in China.

The investigators plan to conduct a large-scale questionnaire survey among PLWH in Zhejiang Province to assess liver function, detect liver Injuries early, and analyze HIV, hepatitis B virus, hepatitis C virus, anti-HIV drugs, alcohol and other factors associate with liver injuries in PLWH, to provide basis for the treatment and prevention of liver disease in PLWH in eastern China.

Inclusion Criteria:

• Age ≥18 years old;
• Non-hospitalized patients diagnosed with HIV infection;
• Sign the informed consent voluntarily.

Exclusion Criteria:

• Severe active infection requiring parenteral antibiotics or antifungal treatment within 30 days before the assessment;
• Other major chronic diseases that may affect health-related quality of life, such as extrahepatic malignant tumors;
• Psychotic patients, patients with severe cognitive or neurological deficits;
• Women during pregnancy and lactation;
• Those who refuse to sign informed consent.

PLWH crowd in Zhejiang Province