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General anesthesia and regional anesthesia can be chosen in cesarean operations. Endotracheal intubation and mechanical ventilation are components of general anesthesia. Endotracheal intubation has been shown to cause increased intracranial pressure. There is not enough information about the effect of spinal anesthesia on intracranial pressure during cesarean operations. Increased intracranial pressure can cause neurological complications by disrupting brain perfusion. For this reason, the investigators think that the safe anesthesia method should be determined especially in pregnant patients who are at risk of increased intracranial pressure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group General Anesthesia | Experimental | C-Section under general anesthesia |
|
| Grup Spinal Anesthesia | Experimental | C-Section under spinal anesthesia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Optic Nerve Sheath Diameter Measurement | Other | The change in intracranial pressure via optic nerve sheath diameter measurement |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Optic Nerve Sheath Diameter | The change in intracranial pressure via optic nerve sheath diameter measurement during c-section among 5 time point. | Throughout the surgery |
| Change in regional cerebral oxygen saturation | The change in regional cerebral oxygen saturation during c-section among 5 time point. | Throughout the surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Perioperative Hemodynamic Parameters | Mean arterial pressure in mmHg | Throughout the surgery |
| Perioperative Hemodynamic Parameters | Heart rate beat per minute |
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Inclusion Criteria:
Exclusion Criteria:
Pregnant and undergoing c-section operation
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| Name | Affiliation | Role |
|---|---|---|
| Mehmet Can Tunalı | Bagcilar Training and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bagcilar Training and Research Hospital | Istanbul | 34200 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18509619 | Background | Geeraerts T, Merceron S, Benhamou D, Vigue B, Duranteau J. Non-invasive assessment of intracranial pressure using ocular sonography in neurocritical care patients. Intensive Care Med. 2008 Nov;34(11):2062-7. doi: 10.1007/s00134-008-1149-x. Epub 2008 May 29. | |
| 21523461 | Background | Bauerle J, Nedelmann M. Sonographic assessment of the optic nerve sheath in idiopathic intracranial hypertension. J Neurol. 2011 Nov;258(11):2014-9. doi: 10.1007/s00415-011-6059-0. Epub 2011 Apr 28. |
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| ID | Term |
|---|---|
| D019586 | Intracranial Hypertension |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Throughout the surgery |
| 17325503 | Background | Yoshitani K, Kawaguchi M, Miura N, Okuno T, Kanoda T, Ohnishi Y, Kuro M. Effects of hemoglobin concentration, skull thickness, and the area of the cerebrospinal fluid layer on near-infrared spectroscopy measurements. Anesthesiology. 2007 Mar;106(3):458-62. doi: 10.1097/00000542-200703000-00009. |