this study is conducted to compare the effect of phototherapy" psoralen plus UVA " bath puva to tap water iontophoresis in the treatment of atopic dermatitis in children.

Sixty children were selected from the department of dermatology, Banha University Hospital. Patients were randomly assigned to (Group- A):- 20 children Patients, aged between 6-16 years old. be treated with Phototherapy, for 3 sessions per week for 8 weeks Plus the traditional medical treatment. which is the betamethasone dipropionate 0.05% " diprolene for 2 times a day for 8 weeks. (Group B): 20 children Patients, in Group-B are treated with tap water iontophoresis, for 8 weeks, 3 sessions /week: the intensity were increased according to the patient's tolerance, for 20 minutes. Plus the traditional medical treatment. (Group -C) the control group will treated by only the traditional medical treatment which is the betamethasone dipropionate 0.05% " diprolene" cream, two times a day for 8 weeks Skin thickness by ultrasonography and Patient Oriented Eczema Measure(POEM) are measured before and after 8 weeks of treatment.

Inclusion Criteria:

• Age between 9 to 16 years.
• Suffering from AD of dyshidrotic as well as dry types of more than 6-months duration
• Traditional types of treatment options, including oral or topical corticosteroids, proved ineffective.

Exclusion Criteria:

• Intolerance history to UV radiation.
• Skin malignancy at the area to be treated.
• Acute infection at the treated area.
• Children received radiotherapy in the area to be treated during the last 6 months.
• Children received corticosteroid therapy topically within 14 days before treatment, or systemic corticosteroids or any immunosuppressive drugs within the last 4 weeks.
• Circulatory and sensory disorders and children with diabetes mellitus.

Data will be shared after 6 month of publication .