Analgesia After Knee Arthroscopy :Dexmedetomidine vs Fentanyl

Comparative Study Between Dexmedetomidine and Fentanyl as an Adjuvant to Intra-articular Bupivacaine for Postoperative Analgesia After Knee Arthroscopy.

The aim of this study is to evaluate analgesic effects Bupivacaine, Bupivacaine plus Dexmedetomidine and Bupivacaine plus Fentanyl in relieving pain after knee arthroscopic surgery.

Forty-five patients ASA I - II aged 21-45 years for elective knee arthroscopy were divided into 3 groups: Group B, BD and BF. Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline. Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug).

Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug). The time of first request of analgesia and analgesic effect by VAS during the first 24 hr. postoperatively are recorded.

Inclusion Criteria:

• Either sex,
• Age 21-45 years,
• American Society of Anesthesia (ASA) I - II for elective knee arthroscopy.

Exclusion Criteria:

• The patients with history of hepatic and renal diseases, psychiatric disorders,
• Prolonged intake of (NSAIDS, opioids and tricyclic antidepressant),
• Allergy to study drugs and patient who received analgesics up to 24 hr. before surgery were excluded from this study.