Effects of tDCS in M1 and DLPFC on Pain Processing in Healthy Volunteers

Effects of Transcranial Direct Current Stimulation on Primary Cortex and Prefrontal Dorsolateral Cortex in Pain Processing on Healthy Volunteers: A Triple Blind Randomized Controlled Trial.

The purpose of this study is to evaluate the effects of a direct current applied transcranial over two cortical areas on healthy volunteers' pain processing.

Inclusion Criteria:

• Age between 18 and 40 years
• Comprehension of the study tasks

Exclusion Criteria:

• Presence of pain in the previous 6 months
• Altered sensitivity in the tested regions
• Intolerance to electrotherapy
• Presence of pacemakers or any other implanted device
• Ulcers or scars in the skin at the location of the electrodes
• Treatment with direct current stimulation within one week
• Pregnancy
• Frequent headaches
• Epilepsy
• History of neuromuscular disease
• Previous clinical history of cervical surgery
• Injuries or surgery affecting the upper limb
• diabetes mellitus
• Cardiovascular diseases
• Oncological diseases
• Consumption of analgesic drugs 7 days before the study