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| Name | Class |
|---|---|
| Cairo University | OTHER |
| National Research Centre, Egypt | OTHER |
| Academy of Scientific Research and Technology, Egypt | OTHER |
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The medical and paramedical staff of the front-line services are potentially exposed to SARS-CoV-2. Therefore, despite the application of standard protective measures, it is possible that a certain number of these personnel have already contracted SARS-CoV-2, including in its asymptomatic form. Serological testing in this context would be useful for deploying immune healthcare workers as to limit the risk of viral infection and transmission. Therefore, it is of utmost importance to prove that the serological response entails the production of neutralizing antibodies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthcare workers (HCWs) |
| ||
| Healthy blood donors and healthy subjects in blood bank |
| ||
| Convalescents |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Specific anti-SARS-CoV-2 antibodies | Biological | A serum sample needs to be collected from each participant upon recruitment into the investigation All samples will be tested by the rapid test (Artron, Artron Laboratories, Burnaby, Canada), IgM / IgG which is an antibody capture Immunochromatografac assay for simultaneous detection of IgM and IgG in serum or plasma for COVID -19 in samples. All samples will be tested for total Immunoglobulins and IgG in samples for COVID-19 virus by Ortho clinical diagnostics chemiluminescent technique (Ortho, Raritan, USA). |
| Measure | Description | Time Frame |
|---|---|---|
| Describe the serological status of individuals in the study by presence of specific anti-SARS-CoV-2 antibodies | 3 Months |
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Inclusion Criteria:
Exclusion Criteria:
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Age-stratified sample from general population with 3 subgroups:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ECRRM | Cairo | 32 | Egypt | |||
| Faculty of Medicine, Cairo University |
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| ID | Term |
|---|---|
| D018352 | Coronavirus Infections |
| ID | Term |
|---|---|
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
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| Cairo |
| Egypt |
| D007239 |
| Infections |