The study is designed to evaluate the safety, operability and efficacy of performing the new tissue containment system during laparoscopic hysterectomy. Pre- and perimenopausal women undergoing laparoscopic hysterectomy.

Inclusion Criteria:

• Pre- and Peri-menopausal woman patient age 18-65 years
• Women with fibroids, adenomyosis, and endometrial hyperplasia and indication for laparoscopic hysterectomy.
• Normal Pap smear result within one year
• The uterus is larger than 12 weeks of gestation
• The body mass index of the patients is 18.5-27.9kg/m2
• Signed informed consent form

Exclusion Criteria:

• Women with Known or suspected malignancy
• patients during pregnancy and lactation
• Known blood diseases, bleeding coagulation disease, any part of the active bleeding or bleeding tendency of the constitution of the patient
• Patients with known severe liver and kidney dysfunction;Liver function (ALT, AST) ≥ 2 times of normal upper limit, or renal function (Cr) ≥ normal upper limit
• Patients who are known to have participated in any other clinical trial within 3 months
• Patients who cannot sign informed consent
• Patients with acute stage infection of the reproductive system or other sites

IPD will to be shared with other researchers after four years