Multimodal Investigation of Intracranial Clot Environment

Multimodal Investigation of Intracranial Clot Environment

Analysis of peri clot blood collected at the acute phase of stroke in order to understand physiopathological mechanisms involved in the cerebrovascular damage

It has been shown that immune cells accumulate around the clot at the acute phase of stroke. Leukocytes and their specific chemokines and cytokines regulation may impact cerebrovascular integrity.

Inclusion criteria:

1. Over 18 years of age,
2. Non-dependent for activities of daily living prior to the onset of the MI (Modified Rankin Score >2)
3. Having an occlusion of a large arterial trunk proven by imaging (angio-MRI or angio-scanner).

Exclusion criteria:

1. Patients initially admitted but for whom endovascular treatment will not finally be performed (re-infusion, catheterization failure...) will be excluded from the study.
2. Major patients under guardianship or curatorship or patients deprived of liberty