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| Name | Class |
|---|---|
| University Hospital, Bordeaux | OTHER |
| University of Tsukuba | OTHER |
| University of London | OTHER |
| University of Amsterdam |
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Current treatment of high-risk Brugada Syndrome (BrS) patients (pts) with recurrent VF is limited. Catheter ablation (CA) has been performed for BrS but a large study with long-term outcomes of CA in BrS ablation are lacking.
Brugada syndrome (BrS) patients who undergo BRS substrate ablations from tertiary centers for catheter ablations of complex arrhythmias from three continents - Asia, Europe and North America - are registered in a common database. The investigators exclude patients who were lost to follow up in the outpatient clinic.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CA BrS | Symptomatic BrS patients who underwent catheter ablation of the BrS/VF substrate |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Catheter Ablation | Procedure | Ventricular fibrillation substrate |
|
| Measure | Description | Time Frame |
|---|---|---|
| Death | Expiration, unrelated to procedure | 3 years |
| ICD Therapy for VT/VF | Electrical therapy delivered through device for termination of VF episodes | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Inappropriate ICD Therapy | Caused by lead sensing or programming errors | 3 years |
| Normalization of Brugada ECG pattern | ECG pattern is normal sinus rhythm after catheter ablation |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who have positive Brugada ECG pattern and have underwent catheter ablation of VF substrates prior to enrollment.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pacific Rim Electrophysiology Research Institute, Chulalongkorn University | Bangkok | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36960730 | Derived | Nademanee K, Chung FP, Sacher F, Nogami A, Nakagawa H, Jiang C, Hocini M, Behr E, Veerakul G, Jan Smit J, Wilde AAM, Chen SA, Yamashiro K, Sakamoto Y, Morishima I, Das MK, Khongphatthanayothin A, Vardhanabhuti S, Haissaguerre M. Long-Term Outcomes of Brugada Substrate Ablation: A Report from BRAVO (Brugada Ablation of VF Substrate Ongoing Multicenter Registry). Circulation. 2023 May 23;147(21):1568-1578. doi: 10.1161/CIRCULATIONAHA.122.063367. Epub 2023 Mar 24. |
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All data published will be deindentified
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| ID | Term |
|---|---|
| D053840 | Brugada Syndrome |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D000075224 | Cardiac Conduction System Disease |
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| ID | Term |
|---|---|
| D017115 | Catheter Ablation |
| ID | Term |
|---|---|
| D000078703 | Radiofrequency Ablation |
| D000078702 | Radiofrequency Therapy |
| D013812 | Therapeutics |
| D055011 | Ablation Techniques |
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| OTHER |
| Ogaki Municipal Hospital | UNKNOWN |
| Indiana University | OTHER |
| Taipei Veterans General Hospital, Taiwan | OTHER_GOV |
| Zhejiang University | OTHER |
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| 3 years |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D013514 |
| Surgical Procedures, Operative |