Determining the treatment strategy for patients with degenerative diseases of the spine is extremely difficult, without an accurate understanding of the nature of stress distribution in the vertebral-motor segments of the spine, as well as biomechanical changes that are associated with degenerative diseases of the spine. In this clinical study, we want to compare the use of unilateral and bilateral transpedicular fixation for treating the patients with degenerative diseases of the lumbar spine.

It is planned to use posterior stabilization without interbody fusion. In the postoperative period, all the patients receive antibacterial and analgesic therapy. The early postoperative period is spent in a hospital. Repeated appearances for control examinations (3, 6, 12 months) are provided for physical examination (EQ-5D, Oswestry Disability Index) and performing radiographs or computed tomography (CT) of the spine. All patients undergo a standard rehabilitation course.

Inclusion Criteria:

• Written informed consent of the patient to participate in the study;
• Patients with degenerative diseases of the lumbar spine.
• The opportunity for observation during the entire study period (12 months);
• Mental adequacy, ability, willingness to cooperate and follow the doctor's recommendations.

Exclusion Criteria:

• The refusal of a patient from surgery
• The presence of contraindications to surgery
• Severe forms of diabetes (glycosylated hemoglobin >9%);
• Blood diseases (thrombopenia, thrombocytopenia, anemia with Hb< 90g\l);
• The unwillingness of the patient to conscious cooperation.