Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics. Acucela is working towards a spectacle-like device (eSPECs), which will have a clear zone for unimpeded central visual tasks and a periphery that provides defocus in order to alter retinal physiology leading to myopia regulation. This study will establish the changes seen during a proof-of-concept that projected defocus in the periphery utilizing a wearable device will stimulate physiological changes similar to those in the literature.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test Arm | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Active projection of defocused image in the peripheral visual field (eSpecs, Acucela Inc.) | Device | For the right/test eye, a defocused image is projected onto the peripheral retina while the subject views a distant, in-focus image |
| Measure | Description | Time Frame |
|---|---|---|
| Axial length (AL) | Change in AL from baseline in the test eye vs. control eye | 1 hour |
| Choroidal thickness (CT) | Change in CT from baseline in the test eye vs. control eye | 1 hour |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Arkady Selenow, OD | Manhattan Vision Associates/Institute of Vision Research | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Manhattan Vision Associates/institute of Vision Research | New York | New York | 10022 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009216 | Myopia |
| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| D005128 | Eye Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| No Active projection of defocused image in the peripheral visual field (eSpecs, Acucela Inc.) | Device | For the left/control eye, no image is projected onto the peripheral retina. The subject views a distant, in-focus image. |
|