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| Name | Class |
|---|---|
| University of Southern California | OTHER |
| American Psychoanalytic Association | UNKNOWN |
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The broad goals of our pilot study are to (1) determine whether psychodynamic psychotherapy for psychosis (PPfP), relative to treatment as usual (TaU), can maintain or augment clinical and functional benefits for patients who have achieved initial recovery in our coordinated specialty care (CSC) early psychosis treatment program; (2) to conduct novel empirical study of how various psychodynamic factors may inform candidate selection, mediate therapeutic effects, and influence relational aspects of the therapy; and (3) to conduct a detailed study of how features of therapist and patient speech and behavior influence therapeutic outcomes, therapeutic alliance alliance, and relational process. This registration focuses on the first goal.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Psychodynamic Psychotheray | Experimental | Following Coordinated Specialty Care, we will offer weekly psychodynamic psychotherapy and medication management sessions which will be conducted solely by the PI, Keith Gallagher, in the initial pilot period. Consent will be obtained to record audio and video of the sessions |
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| Treatment as Usual | Active Comparator | Following Coordinated Specialty Care, patients will be referred to general mental health providers in the community, which would typically include less intensive and frequent psychotherapy by a social worker or psychologist as well as medication management by a psychiatrist who may not be a specialist in psychotic disorders. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Psychodynamic Psychotherapy | Behavioral | Intensive psychotherapy that is psychodynamically oriented. |
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| Measure | Description | Time Frame |
|---|---|---|
| Overall Symptom Severity | The Positive and Negative Symptom Scale (PANSS) will be used. This is a 30 item scale. Each item is measured on a 7-point scale from 1 (absent) to 7 (extreme). Items are summed to obtain an overall score. | From enrollment up to 5 years from enrollment. |
| Overall Functioning - Social | The Global Functioning: Social scale will be used, with symptoms rated 1 (most impaired) to 10 (superior functioning). | From enrollment up to 5 years from enrollment. |
| Overall Functioning - Role | The Global Functioning: Role scale will be used, with symptoms rated 1 (most impaired) to 10 (superior functioning). | From enrollment up to 5 years from enrollment. |
| Measure | Description | Time Frame |
|---|---|---|
| Symptom Severity (Positive Symptoms) | The positive symptoms subscale of the Positive and Negative Symptom Scale (PANSS) will be used. Each item is measured on a 7-point scale from 1 (absent) to 7 (extreme). Subscale items are summed to obtain a positive symptom score. | From enrollment up to 5 years from enrollment. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Keith Gallagher, MD | Yale University | Principal Investigator |
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| ID | Term |
|---|---|
| D011618 | Psychotic Disorders |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D064889 | Psychotherapy, Psychodynamic |
| ID | Term |
|---|---|
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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| Usual Care | Behavioral | Conventional treatment offered in the community. |
|
| Symptom Severity (Negative Symptoms) |
The negative symptoms subscale of the Positive and Negative Symptom Scale (PANSS) will be used. Each item is measured on a 7-point scale from 1 (absent) to 7 (extreme). Subscale items are summed to obtain an overall score. |
| From enrollment up to 5 years from enrollment. |