Ionized Magnesium for Monitoring of Citrate-anticoagulated CVVHD

Importance of Ionized Magnesium Measurement for Monitoring of Continuous Venovenous Haemodialysis With Citrate Anticoagulation

It has been reported in several studies that ionized hypomagnesemia is associated with higher morbidity and mortality rates. During continuous renal replacement therapy with regional citrate anticoagulation (CRRT-RCA), the loss of magnesium has been reported to not be covered by magnesium concentration in ordinary dialysis fluid. This may lead to ionized hypomagnesemia. However the incidence of ionized hypomagnesemia in patients requiring CRRT-RCA remains unclear and need to be estimated to determine if ionized magnesium monitoring could be of interest. This study aim to assess the incidence of ionized hypomagnesemia induced by CRRT-RCA.

Inclusion criteria:

• Consecutive patients admitted to the ICU and requiring continuous renal replacement therapy with regional citrate anticoagulation
• age > 18 ans

Exclusion criteria:

• Persons under protection
• Paritcipation rejections