Vienna Versus SARS-CoV-2 Virus Study

Vienna Versus SARS-CoV-2 Virus: A Prospective Large-scale Antibody Study of SARS-CoV-2 in Patients and Health Care Workers

This study examines the seroprevalence against SARS-CoV-2 in health care workers and patients at the Vienna General Hospital.

This study consists of 2 parts: a longitudinal study enrolling 3,000 health care professionals at the Vienna General Hospital testing their antibody status 6 times over a period of 12 months (Cohort A), and a serial cross-sectional study of 3,000 patients (i.e., a total of 9,000 patients) admitted to the Vienna General Hospital for non-COVID-19-related symptoms at 3 different time points during this pandemic (Cohort B).

Cohort A:

Inclusion criteria:

• Physicians
• Nursing staff
• Midwives
• Medical-technical assistants (including medical, therapeutic and diagnostic healthcare staff, and medical and nursing assistants)
• Administrative personnel with patient contact

Exclusion Criteria:

• Not employed at the Medical University of Vienna or the Vienna General Hospital
• No signed informed consent

Cohort B:

Inclusion Criteria:

● Patients with available residual serum samples

Exclusion Criteria:

● Serum samples from COVID-19 triage units at the Vienna General Hospital