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| Name | Class |
|---|---|
| University of Medicine 1 Yangon | OTHER |
| Physical Medicine and Rehabilitation, Yangon General Hospital | UNKNOWN |
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To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis
Knee osteoarthritis is a common disorder affecting elderly and obese. Currently, there are 3 types of treatment; pharmacological, non-pharmacological and surgery. Though ultrasound, a non-pharmacological treatment, is increasingly used in knee osteoarthritis, the advantages and disadvantages of low intensity pulsed ultrasound (LIPUS) and high intensity continuous ultrasound (HICUS) are yet to be clarified. Therefore, a randomized control trial will be done to compare LIPUS and HICUS in participants with knee osteoarthritis presenting to Department of Physical Medicine and Rehabilitation, Yangon General Hospital, Myanmar.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low intensity pulsed ultrasound | Experimental | Participants in this arm will receive low intensity pulsed ultrasound therapy on the affected knees for 20 minutes per day, 5 days a week for 4 weeks. Conventional physiotherapy of quadriceps muscle exercise and health education about life style will also be given. |
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| High intensity continuous ultrasound | Active Comparator | Participants in this arm will receive high intensity continuous ultrasound therapy on the affected knees for 10 minutes per day, 5 days a week for 4 weeks. Conventional physiotherapy of quadriceps muscle exercise and health education about life style will also be given. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low intensity pulsed ultrasound | Device | Low intensity pulsed ultrasound therapy will use ultrasound with frequency of 1.5 MHz, power intensity of 30 mW/cm^2 (0.03 W/cm^2 ) and 20% duty cycle. |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale (VAS) | It is one of the most commonly used measures of pain intensity and it is divided into 10 ordinal ratings with 0 being "no pain" and 10 being "pain as bad as it could be". | 8 weeks |
| Western Ontario McMaster University Osteoarthritis Index Inventory (WOMAC) | This index measures clinically important symptoms of pain, stiffness and function. It consists of 23 questions (5 pain, 2 stiffness and 16 physical function) and the maximum score is 100, indicating the worst outcome while the minimum score is 0, indicating the best outcome. | 8 weeks |
| Percentage of participants with skin irritation | Skin irritation, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent). | 8 weeks |
| Percentage of participants with tingling | Tingling sensation, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent). | 8 weeks |
| Percentage of participants with oedema | Oedema, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent). | 8 weeks |
| Percentage of participants with burns | Burns, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent). | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Wunn Lei Thwe, M.B.,B.S | Contact | +959786478599 | wunnleithwe92@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Khin Myo Hla, PhD M.B.,B.S | Physical Medicine and Rehabilitation Department, Yangon General Hospital | Study Chair |
| Soe Soe Khaing, PhD M.B.,B.S | Physical Medicine and Rehabilitation Department, Yangon General Hospital |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Physical Medicine and Rehabilitation, Yangon General Hospital | Recruiting | Yangon | Burma |
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| High intensity continuous ultrasound | Device | High intensity continuous ultrasound therapy will use ultrasound with frequency of 1 MHz, power intensity of 3 W/cm^2 and 100% duty cycle. |
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|
| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| D010003 | Osteoarthritis |
| D012216 | Rheumatic Diseases |
| D009140 | Musculoskeletal Diseases |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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