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Study of the cause of lymphopenia in Covid19 viral infection will be done in 3 cohorts. First cohort will be patients asymptomatic or with mild symptoms. Second cohort will be patients with severe illness and admitted to ICU. Third cohort will be patients critically ill and on artificial ventilation.
Each cohort will include 30 patients. Complete blood count in all patients will be done daily in all patients. Bone marrow aspiration cytology will be done in some selected patients especially those with lymphopenia less than 1000 per cubic mm.
Correlation of the degree of lymphopenia with the status of the patients will be done. Also correlation will be done about the relation of recovery of lymphopenia and status of the patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Asymptomatic or mild symptoms patients patients | Patients with no or mild symptoms and need no respiratory support. |
| |
| Severe symptoms patients | Patients who need admission to ICU because he needs oxygen by nasal canula and needs drugs whether azthromycin or remdesivir according to treatment protocol. |
| |
| Critically ill patients | Patients who need artificial ventilation because of many causes and may need plasma from convalescent patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Complete blood picture, bone marrow aspiration cytology | Diagnostic Test | none except the regular routine investigations in such cases |
|
| Measure | Description | Time Frame |
|---|---|---|
| Death or recovery | Follow up | Up to 24 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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All patients admitted with the diagnosis off Covid19 viral infection of all ages and all ethnic backgrounds and agree about the study
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Institute Cairo University | Cairo | Egypt |
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| ID | Term |
|---|---|
| D008231 | Lymphopenia |
| ID | Term |
|---|---|
| D007970 | Leukopenia |
| D000095542 | Cytopenia |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| D007960 |
| Leukocyte Disorders |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |