Laser Interferometry of Single Virus Particles Flowing Through Glass Microcapillaries to Detect Novel Coronavirus COVID-19
Laser Interferometry of Single Virus Particles Flowing Through Glass Microcapillaries to Detect Novel Coronavirus COVID-19
Using Laser light to detect COVID 19 virus particles in deep throat swab / nasal swab samples.
The investigators will develop novel primers to detect single virus particles in patient samples. The method involves the absorption of light by single virus particles giving a specific pattern. The investigators will develop the device to create a microdroplet of carrier fluid that is run through the trial device. The investigators will develop novel binding receptors for preferential capture of Coronavirus.
The investigators will review the results of the novel test against the standard diagnostic test and identify virus particles in test negative subjects.
The investigators will isolate the viral rna in test negative subjects and perform sequencing to find novel mutations that are not detected by the current test.
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