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We hypothesize that serial changes of body composition in patients with pneumonia can help clinician to monitor prognosis. It was associated with underlying immune response.
Specific aims:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| noninvasively Bio-electrical Impedance Analysis (BIA) | Device | By means of noninvasively Bio-electrical Impedance Analysis (BIA) to measure body composition, which divides body weight into different components such as lean body mass and fat mass. |
| Measure | Description | Time Frame |
|---|---|---|
| ICU Days | length of stay in ICU | During hospitalization， "through study completion, an average of 1 year" |
| Ventilation days | days of mechanical ventilation | up to 24 weeks |
| sepsis free days | the cure day of sepsis | up to 24 weeks |
| mortality | death rate | During hospitalization， "through study completion, an average of 1 year" |
| Change in Total Body Water | Change in Total Body Water | Change from Baseline Total Body Water at day 8 |
| Change in Percentage of Body Fat | Change in Percentage of Body Fat | Change from Baseline Percentage of Body Fat at day 8 |
| Change in Soft Lean Mass | Change in Soft Lean Mass | Change from Baseline Soft Lean Mass at day 8 |
| Change in segment/monocyte ratio | Change in Segment count to monocyte count ratio | Change from Baseline Segment count to monocyte count ratio at day 8 |
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Inclusion Criteria:
Adult patients with pneumonia admitted to the thoracic ward or medical intensive care unit of Kaohsiung Chang Gung Memorial Hospital
Exclusion Criteria:
-
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Adult patients with pneumonia admitted to the thoracic ward or medical intensive care unit of the Kaohsiung Chang Gung Memorial Hospital
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| Name | Affiliation | Role |
|---|---|---|
| WEN-FENG Fang | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaohsiung Chang Gung Memorial Hospital | Kaohsiung City | 83301 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24806181 | Background | Wunderink RG, Waterer GW. Community-acquired pneumonia. N Engl J Med. 2014 May 8;370(19):1863. doi: 10.1056/NEJMc1402692. No abstract available. | |
| 25830421 | Background | Postma DF, van Werkhoven CH, van Elden LJ, Thijsen SF, Hoepelman AI, Kluytmans JA, Boersma WG, Compaijen CJ, van der Wall E, Prins JM, Oosterheert JJ, Bonten MJ; CAP-START Study Group. Antibiotic treatment strategies for community-acquired pneumonia in adults. N Engl J Med. 2015 Apr 2;372(14):1312-23. doi: 10.1056/NEJMoa1406330. |
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There is no plan to disclose information about individual patients
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| ID | Term |
|---|---|
| D011014 | Pneumonia |
| D018805 | Sepsis |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| D018746 |
| Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |