Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth

Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth (A Randomized Controlled Clinical Trial)

The aim of the present study is to assess clinically and radio-graphically the regenerative potential of immature permanent teeth with necrotic pulp using blood clot and Platelet rich fibrin scaffolds.

30 immature necrotic permanent teeth in patients will be allocated and divided into two groups. Group 1 will be treated by regenerative procedure using blood clot as a scaffold and Group 2 will be treated with regenerative procedures using combined blood clot and Platelet rich fibrin as a scaffold.

Inclusion Criteria:

• Necrotic incisors with immature roots
• Pulp space not needed for post and core.
• The patient has to be free from any coagulation disorders, with normal platelets count.
• Good oral hygiene
• Cooperative patient

Exclusion Criteria:

• Internal or external root resorption.
• Root fracture and/or alveolar fracture.
• Previous root canal treatment.
• Medically compromised patients
• Uncooperative patient